Evolution of the immune system in humans from infancy to old age
AK Simon, GA Hollander… - Proceedings of the …, 2015 - royalsocietypublishing.org
AK Simon, GA Hollander, A McMichael
Proceedings of the Royal Society B: Biological Sciences, 2015•royalsocietypublishing.orgThis article reviews the development of the immune response through neonatal, infant and
adult life, including pregnancy, ending with the decline in old age. A picture emerges of a
child born with an immature, innate and adaptive immune system, which matures and
acquires memory as he or she grows. It then goes into decline in old age. These changes
are considered alongside the risks of different types of infection, autoimmune disease and
malignancy.
adult life, including pregnancy, ending with the decline in old age. A picture emerges of a
child born with an immature, innate and adaptive immune system, which matures and
acquires memory as he or she grows. It then goes into decline in old age. These changes
are considered alongside the risks of different types of infection, autoimmune disease and
malignancy.
This article reviews the development of the immune response through neonatal, infant and adult life, including pregnancy, ending with the decline in old age. A picture emerges of a child born with an immature, innate and adaptive immune system, which matures and acquires memory as he or she grows. It then goes into decline in old age. These changes are considered alongside the risks of different types of infection, autoimmune disease and malignancy.
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