Topical chemotherapy and immunotherapy of mycosis fungoides: intermediate-term results
EC Vonderheid, EJ Van Scott, WC Johnson… - Archives of …, 1977 - jamanetwork.com
• A group of 220 patients with mycosis fungoides (MF) and other lymphomatous diseases
was treated with sustained topical applications of dilute aqueous solutions of
mechlorethamine hydrochloride for intervals ranging in excess of seven years. Response to
treatment, immunologic responsiveness, and subsequent course and survival were
inversely related to magnitude of disease at time of starting treatment. Relapses were
common, and in most instances were related to failure of maintenance of topical therapy …
was treated with sustained topical applications of dilute aqueous solutions of
mechlorethamine hydrochloride for intervals ranging in excess of seven years. Response to
treatment, immunologic responsiveness, and subsequent course and survival were
inversely related to magnitude of disease at time of starting treatment. Relapses were
common, and in most instances were related to failure of maintenance of topical therapy …
