The where, what and why of the developing renal stroma
LA Cullen-McEwen, G Caruana… - Nephron Experimental …, 2005 - karger.com
LA Cullen-McEwen, G Caruana, JF Bertram
Nephron Experimental Nephrology, 2005•karger.comIn recent years, a great deal has been learnt about the molecular regulation of kidney
development. While most research has focused on the molecular regulation of ureteric
branching morphogenesis and nephron formation, significant insights into the definition and
functions of the renal stroma have emerged. Many molecules expressed in the developing
renal stroma are now known to play significant regulatory roles in kidney development.
However, the term 'renal stroma'continues to have different meanings to different …
development. While most research has focused on the molecular regulation of ureteric
branching morphogenesis and nephron formation, significant insights into the definition and
functions of the renal stroma have emerged. Many molecules expressed in the developing
renal stroma are now known to play significant regulatory roles in kidney development.
However, the term 'renal stroma'continues to have different meanings to different …
Abstract
In recent years, a great deal has been learnt about the molecular regulation of kidney development. While most research has focused on the molecular regulation of ureteric branching morphogenesis and nephron formation, significant insights into the definition and functions of the renal stroma have emerged. Many molecules expressed in the developing renal stroma are now known to play significant regulatory roles in kidney development. However, the term ‘renal stroma’continues to have different meanings to different researchers. This review clarifies this situation and defines the derivation, location and functions of the stroma in the developing metanephros.
Karger